Murder seems to follow Jessica Fletcher, a former English teacher and a mystery writer full of charm, zest-for-life, and personality; who happens to become "the investigator" when traveling around the country to promote a series of novels. Murder always occurs when she is present. Even in Cabot Cove! Although Angela Lansbury was the only regular character throughout the series entire run, she was frequently joined by a number of recurring and special guest stars, including Tom Bosley as Sheriff Amos Tupper in the early seasons and Ron Masak as Sheriff Mort Metzger in the later seasons, William Windom as Dr. Seth Hazlitt, Michael Horton as her nephew Grady Fletcher (one of her many, many relatives), and from time to time Jerry Orbach would appear as private eye Harry McGraw. Orbach's role later led into a short-lived spin-off, The Law & Harry McGraw. The series aired a total of 263 color episodes from 7 October 1984 through 19 May 1996 and five telemovies (including the pilot movie, which aired in September of 1984). As of the fall of 2009, 10 seasons have been released on DVD, with the 11th season due to be released in early 2010.

A security android (Alexander Skarsgård) hides its sentience as it works on risky jobs, even though all it wants to do is watch soap operas in the sci-fi thriller/comedy based on The Murderbot Diaries book series by Martha Wells.

In this adaptation of the British series, Murder in Successville, each episode features Homicide Detective Terry Seattle (Will Arnett) with a new murder case and a new guest star as his partner. With no script, Kumail Nanjiani, Conan O'Brien, Annie Murphy, Sharon Stone, Ken Jeong, and Marshawn Lynch must improvise and try to figure out the killer.

18-year-old Nancy Drew (Kennedy McMann) was ready to leave for college when the death of her mother delays her plans and she becomes involved in a murder investigation in the series based on the classic mystery novels.

From Donald P. Bellisario comes NCIS, a show bringing us the inner workings of the government agency that investigates all crimes involving Navy and Marine Corps personnel, regardless of rank or position. From murder and espionage to terrorism and stolen submarines, these special agents traverse the globe to investigate all crimes with Navy or Marine Corps ties. Leading this team that operates outside of the military chain of command is Special Agent Leroy Jethro Gibbs (Mark Harmon), a skilled investigator and interrogator who is smart, tough and willing to bend the rules to get the job done. Working under Gibbs is Special Agent Tony DiNozzo (Michael Weatherly), a former homicide detective who has instincts that can come only from working on the streets. Joining them is Abby Sciuto (Pauley Perrette), a gifted forensics specialist whose dark wit matches her goth-style hair and clothes, and Dr. Donald "Ducky" Mallard (David McCallum), a medical examiner. Through season one a new character has been introduced -- special agent Tim McGee (Sean Murray, "The Random Years") whose computer skills will be a very big part of the NCIS team. Special Agent Caitlin "Kate" Todd (Sasha Alexander, "Dawson's Creek"), a former United States Secret Service agent, has brought her intelligence and gutsy personality to the team through first 2 seasons, until during her duty in season two finale, when she was murdered by a terrorist. In season three, the NCIS team welcomed Mossad Agent Ziva David (Cote de Pablo), who took Kate's place in the team, and the NCIS team got a new director, Jenny Shepard (Lauren Holly). After Holly's departure at the end of Season 5, the position of the NCIS director was taken over by Leon Vance (Rocky Carroll).