Once you've figured out the broad parts of how to save people, it becomes harder and harder to get the details you would like right. I spent an exorbitant amount of time trying to get Tom and Jenny to have an argument about the right thing on the right day, to no avail. It is extremely likely you'll reach a point that you go, "Fuck it, just let 'em burn!", probably more than once, at which point you should turn the game off and leave it for a day or so. This isn't a game that you should pick at for hours. It's one to put back up the shelf for a bit, until you can take it down and look at the problem with fresh eyes. You have all the time you need. Sort of.