Lori Loughlin

Biography: With pretty, girl-next-door looks and a sweet smile, this small-screen actress inspired countless boyhood crushes as John Stamos's main squeeze on the family sitcom Full House. A child model and former teen soap star, Loughlin appeared in a number of TV-movies before she landed a six-episode stint on Full House, but her character proved so popular, she ended up staying for eight seasons. During her tenure, she continued to star in myriad Lifetime-type telepics, invariably playing plucky young women who overcome adversity and abuse. Although none of her subsequent series recaptured her seminal success—not even the WB drama Summerland, which she created and produced as a showcase for her talents—Loughlin remained a familiar TV face, with guest spots on numerous series and a lead in the CW spin-off 90210.